	{"id":4708,"date":"2015-03-24T14:52:30","date_gmt":"2015-03-24T07:52:30","guid":{"rendered":"http:\/\/science-technology.vn\/?p=4708"},"modified":"2015-03-24T14:52:30","modified_gmt":"2015-03-24T07:52:30","slug":"cong-nghe-sinh-hoc-bien-gioi-moi","status":"publish","type":"post","link":"https:\/\/science-technology.vn\/?p=4708","title":{"rendered":"C\u00f4ng ngh\u1ec7 sinh h\u1ecdc: bi\u00ean gi\u1edbi m\u1edbi"},"content":{"rendered":"<p>Sau khi \u0111\u0103ng b\u00e0i: \u201cCu\u1ed9c c\u00e1ch m\u1ea1ng m\u1edbi trong C\u00f4ng ngh\u1ec7\u201d nhi\u1ec1u sinh vi\u00ean \u0111\u00e3 h\u1ecfi t\u00f4i v\u1ec1 m\u1ed1i quan h\u1ec7 gi\u1eefa Sinh h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7 th\u00f4ng tin, hai l\u0129nh v\u1ef1c kh\u00e1c nhau ho\u00e0n to\u00e0n. L\u0129nh v\u1ef1c Sinh h\u1ecdc \u0111\u00e3 thay \u0111\u1ed5i l\u1edbn xem nh\u01b0 k\u1ebft qu\u1ea3 c\u1ee7a D\u1ef1 \u00e1n H\u1ec7 gen con ng\u01b0\u1eddi n\u0103m 2000. Ng\u00e0y nay c\u00e1c nh\u00e0 khoa h\u1ecdc coi Sinh h\u1ecdc nh\u01b0 khoa h\u1ecdc th\u00f4ng tin, DNA v\u1ec1 c\u0103n b\u1ea3n l\u00e0 ng\u00f4n ng\u1eef b\u1ed1n ch\u1eef s\u1ed1 th\u1ee9c (C,T,G,A) l\u01b0u th\u00f4ng tin tr\u00ean nhi\u1ec5m s\u1eafc th\u1ec3 t\u01b0\u01a1ng t\u1ef1 nh\u01b0 s\u1ed1 nh\u1ecb ph\u00e2n (0,1) trong ng\u00f4n ng\u1eef m\u00e1y t\u00ednh. Do \u0111\u00f3, gen di\u1ec5n \u0111\u1ea1t b\u1ea3n th\u00e2n ch\u00fang h\u1ec7t nh\u01b0 m\u00e1y t\u00ednh th\u1ef1c hi\u1ec7n ch\u01b0\u01a1ng tr\u00ecnh ph\u1ea7n m\u1ec1m. Nh\u1eefng c\u00e1ch di\u1ec5n \u0111\u1ea1t n\u00e0y t\u00edch h\u1ee3p v\u1edbi nh\u1eefng c\u00e1ch kh\u00e1c \u0111\u1ec3 t\u1ea1o ra m\u1ed9t lo\u1ea1i &#8220;l\u1ed1i m\u00f2n th\u00f4ng tin&#8221; m\u00e0 b\u00e1o hi\u1ec7u cho th\u00e2n th\u1ec3 th\u1ef1c hi\u1ec7n ch\u1ee9c n\u0103ng n\u00e0o \u0111\u00f3.<\/p>\n<p>B\u1ea5t k\u00ec c\u00e1i g\u00ec sai v\u1edbi nh\u1eefng l\u1ed1i m\u00f2n n\u00e0y \u0111\u1ec1u t\u1ea1o ra v\u1ea5n \u0111\u1ec1 hay b\u1ec7nh t\u1eadt. B\u1eb1ng vi\u1ec7c hi\u1ec3u c\u00e1ch c\u00e1c gen n\u00e0y l\u00e0m vi\u1ec7c, ch\u00fang ta c\u00f3 th\u1ec3 nh\u00ecn v\u00e0o b\u1ec7nh t\u1eadt t\u1eeb c\u1ea3nh quan kh\u00e1c. B\u1eb1ng vi\u1ec7c hi\u1ec3u c\u00e1c gen chi ti\u1ebft d\u1eabn t\u1edbi b\u1ec7nh t\u1eadt, ch\u00fang ta c\u00f3 th\u1ec3 d\u1ef1 b\u00e1o l\u1ecbch s\u1eed s\u1ee9c kho\u1ebb v\u00e0 \u0111i\u1ec1u \u0111\u00f3 c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i c\u00e1ch ch\u00fang ta x\u1eed tr\u00ed v\u1edbi b\u1ec7nh t\u1eadt ng\u00e0y nay. B\u00ean trong th\u00e2n th\u1ec3 ch\u00fang ta, c\u00f3 h\u00e0ng ngh\u00ecn t\u1ec9 &#8220;l\u1ed1i m\u00f2n th\u00f4ng tin&#8221; li\u00ean n\u1ed1i t\u1ea1o n\u00ean m\u1ea1ng l\u01b0\u1edbi. \u0110\u1ec3 hi\u1ec3u c\u00e1ch nh\u00ecn m\u1edbi n\u00e0y v\u1ec1 sinh h\u1ecdc, ch\u00fang ta ph\u1ea3i hi\u1ec3u nh\u1eefng th\u00f4ng tin n\u00e0y \u1edf c\u00e1c m\u1ee9c kh\u00e1c nhau, t\u1eeb t\u1ebf b\u00e0o t\u1edbi c\u01a1 quan \u0111\u1ec3 cho ch\u00fang ta c\u00f3 th\u1ec3 hi\u1ec3u c\u00e1ch ch\u00fang v\u1eadn h\u00e0nh. N\u1ebfu ch\u00fang ta hi\u1ec3u nh\u1eefng &#8220;l\u1ed1i m\u00f2n th\u00f4ng tin&#8221; n\u00e0y, ch\u00fang ta c\u00f3 kh\u1ea3 n\u0103ng thay \u0111\u1ed5i ch\u00fang do v\u1eady ng\u0103n c\u1ea3n b\u1ec7nh t\u1eadt kh\u1ecfi x\u1ea3y ra. \u0110\u00e2y l\u00e0 b\u1eaft \u0111\u1ea7u c\u1ee7a nguy\u00ean l\u00ed kh\u00e1m ph\u00e1 thu\u1ed1c m\u1edbi.<\/p>\n<p>Ng\u00e0y nay c\u00f3 s\u1ef1 h\u1ee3p l\u01b0u c\u1ee7a Sinh h\u1ecdc v\u00e0 C\u00f4ng ngh\u1ec7 th\u00f4ng tin v\u00e0o m\u1ed9t l\u0129nh v\u1ef1c m\u1edbi t\u00ean l\u00e0 C\u00f4ng ngh\u1ec7 sinh h\u1ecdc v\u00ec m\u1ecdi t\u01b0\u01a1ng t\u00e1c b\u00ean trong th\u00e2n th\u1ec3 ch\u00fang ta th\u1ef1c s\u1ef1 l\u00e0 v\u1ea5n \u0111\u1ec1 c\u00f4ng ngh\u1ec7 th\u00f4ng tin (CNTT). \u0110\u00f3 l\u00e0 l\u00ed do t\u1ea1i sao t\u00f4i tin m\u1ecdi nh\u00e0 khoa h\u1ecdc c\u00f4ng ngh\u1ec7 sinh h\u1ecdc t\u01b0\u01a1ng l\u1ea1i \u0111\u1ec1u n\u00ean c\u00f3 tri th\u1ee9c v\u1ec1 m\u00e1y t\u00ednh \u0111\u1ec3 l\u00e0m vi\u1ec7c theo nghi\u00ean c\u1ee9u c\u1ee7a h\u1ecd. N\u1ebfu ch\u00fang ta c\u00f3 th\u1ec3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c h\u1ec7 th\u1ed1ng th\u00e2n th\u1ec3 qua m\u00f4 h\u00ecnh ho\u00e1 to\u00e1n h\u1ecdc ch\u00fang ta c\u00f3 th\u1ec3 d\u1ef1 b\u00e1o m\u1ed9t s\u1ed1 thu\u1ed9c t\u00ednh n\u1ed5i l\u00ean, v\u00e0 l\u00e0m ra \u0111\u1ed9t ph\u00e1 trong c\u00e1ch ch\u00fang ta gi\u1ea3i quy\u1ebft b\u1ec7nh t\u1eadt. T\u1ea5t nhi\u00ean, th\u00e2n th\u1ec3 ch\u00fang ta l\u00e0 m\u1ed9t h\u1ec7 th\u1ed1ng ph\u1ee9c t\u1ea1p v\u00e0 ch\u00fang ta ch\u1ec9 m\u1edbi b\u1eaft \u0111\u1ea7u kh\u00e1m ph\u00e1 n\u00f3 t\u1eeb g\u00f3c \u0111\u1ed9 m\u1edbi c\u1ee7a c\u00f4ng ngh\u1ec7 th\u00f4ng tin. Ng\u00e0y nay trong m\u1ecdi ph\u00f2ng th\u00ed nghi\u1ec7m nghi\u00ean c\u1ee9u, c\u00f3 nhi\u1ec1u th\u00f4ng tin s\u1eb5n c\u00f3, m\u1ed9t s\u1ed1 l\u01b0u \u1edf c\u00e1c c\u01a1 s\u1edf d\u1eef li\u1ec7u kh\u00e1c nhau, m\u1ed9t s\u1ed1 \u1edf c\u00e1c m\u00e1y t\u00ednh c\u00e1 nh\u00e2n, v\u00e0 ch\u00fang \u0111\u00e3 kh\u00f4ng \u0111\u01b0\u1ee3c t\u00edch h\u1ee3p, t\u1ed5 ch\u1ee9c, ph\u00e2n lo\u1ea1i cho nghi\u00ean c\u1ee9u th\u00eam n\u1eefa. \u0110\u00e2y l\u00e0 ch\u1ed7 t\u00f4i ngh\u0129 c\u00f4ng ngh\u1ec7 th\u00f4ng tin c\u00f3 th\u1ec3 gia t\u0103ng gi\u00e1 tr\u1ecb. Ngay c\u1ea3 b\u1ed9 n\u00e3o c\u1ee7a ch\u00fang ta c\u0169ng b\u1ecb gi\u1edbi h\u1ea1n, ch\u00fang ta kh\u00f4ng th\u1ec3 x\u1eed l\u00ed th\u00f4ng tin l\u1edbn v\u00e0 ph\u1ee9c t\u1ea1p nh\u01b0ng m\u00e1y t\u00ednh l\u1ea1i c\u00f3 th\u1ec3. N\u00f3 c\u00f3 th\u1ec3 x\u1eed l\u00ed h\u00e0ng t\u1ec9 d\u1eef li\u1ec7u, ph\u00e2n lo\u1ea1i qua h\u00e0ng ngh\u00ecn b\u00e0i b\u00e1o \u0111\u1ec3 t\u00ecm ra \u0111i\u1ec1u ch\u00fang ta \u0111ang t\u00ecm. V\u1edbi vi\u1ec7c d\u00f9ng m\u00e1y t\u00ednh v\u00e0 c\u00e1c thu\u1eadt to\u00e1n ph\u1ee9c t\u1ea1p, ch\u00fang ta c\u00f3 th\u1ec3 ti\u1ebft ki\u1ec7m kh\u1ed1i l\u01b0\u1ee3ng l\u1edbn th\u1eddi gian trong nghi\u00ean c\u1ee9u. Thay v\u00ec d\u00e0nh h\u00e0ng tu\u1ea7n h\u00e0ng th\u00e1ng t\u00ecm th\u00f4ng tin m\u00e0 ch\u00fang ta c\u1ea7n, ch\u00fang ta c\u00f3 th\u1ec3 d\u00f9ng ph\u1ea7n m\u1ec1m m\u00e1y t\u00ednh \u0111\u1ec3 ph\u00e2n lo\u1ea1i v\u00e0 thu \u0111\u01b0\u1ee3c d\u1eef li\u1ec7u \u0111\u00fang, v\u00e0o l\u00fac \u0111\u00fang, cho ng\u01b0\u1eddi \u0111\u00fang.<\/p>\n<p>N\u0103m n\u0103m tr\u01b0\u1edbc, t\u00f4i \u0111\u00e3 t\u1ea1o ra ch\u01b0\u01a1ng tr\u00ecnh Ph\u00e1t ki\u1ebfn C\u00f4ng ngh\u1ec7 sinh h\u1ecdc t\u1ea1i Carnegie Mellon \u0111\u1ec3 \u00e1p d\u1ee5ng c\u00f4ng ngh\u1ec7 th\u00f4ng tin t\u1ea1o kh\u1ea3 n\u0103ng cho sinh h\u1ecdc v\u00e0 c\u00e1c l\u0129nh v\u1ef1c li\u00ean quan s\u00e1ng t\u1ea1o ra ph\u00e1t ki\u1ebfn c\u00f3 gi\u00e1 tr\u1ecb, \u0111i\u1ec1u s\u1ebd gi\u00fap cho c\u00e1c nh\u00e0 khoa h\u1ecdc l\u00e0m c\u00f4ng vi\u1ec7c c\u1ee7a h\u1ecd nhanh h\u01a1n v\u00e0 t\u1ed1t h\u01a1n. N\u1ebfu ch\u00fang ta nh\u00ecn l\u1ea1i, ch\u00fang ta c\u00f3 th\u1ec3 th\u1ea5y r\u1eb1ng c\u00f4ng ngh\u1ec7 th\u00f4ng tin \u0111\u00e3 d\u1eabn t\u1edbi nh\u1eefng thay \u0111\u1ed5i l\u1edbn ngang qua mi\u1ec1n \u0111a d\u1ea1ng c\u00e1c b\u1ed9 m\u00f4n. K\u1ebf to\u00e1n, t\u00e0i ch\u00ednh v\u00e0 ch\u1ebf t\u1ea1o \u0111\u01b0\u1ee3c l\u1ee3i ph\u1ea7n l\u1edbn t\u1eeb t\u1ef1 \u0111\u1ed9ng ho\u00e1 ph\u1ea7n m\u1ec1m trong nh\u1eefng n\u0103m 1970 v\u00e0 1980. Trong nh\u1eefng n\u0103m 1990, ti\u1ebfn b\u1ed9 trong c\u00f4ng ngh\u1ec7 truy\u1ec1n th\u00f4ng \u0111\u00e3 gi\u00fap \u0111\u1ecbnh ngh\u0129a l\u1ea1i c\u00e1ch c\u00e1c doanh nghi\u1ec7p qu\u1ea3n l\u00ed nh\u00e0 kho c\u1ee7a h\u1ecd, d\u00e2y chuy\u1ec1n cung c\u1ea5p v\u00e0 c\u00e1ch ch\u00fang c\u00f3 quan h\u1ec7 v\u1edbi kh\u00e1ch h\u00e0ng c\u1ee7a h\u1ecd. Nhi\u1ec1u trong nh\u1eefng c\u00f4ng ngh\u1ec7 v\u00e0 ph\u00e1t ki\u1ebfn n\u00e0y \u0111\u00e3 ti\u1ebfn ho\u00e1 t\u1eeb c\u00e1c y\u1ebfu t\u1ed1 l\u00e0m kh\u00e1c bi\u1ec7t c\u1ea1nh tranh t\u1edbi c\u00e1c n\u0103ng l\u1ef1c c\u1ea7n thi\u1ebft m\u00e0 b\u00e2y gi\u1edd l\u00e0 b\u1ea3n ch\u1ea5t cho c\u00e1c v\u1eadn h\u00e0nh c\u1ee7a h\u1ea7u h\u1ebft c\u00e1c c\u00f4ng ti.<\/p>\n<p>Tuy nhi\u1ec1u ng\u00e0nh c\u00f4ng nghi\u1ec7p \u0111\u00e3 n\u1eafm l\u1ea5y c\u00f4ng ngh\u1ec7 th\u00f4ng tin nh\u01b0 m\u1ed9t y\u1ebfu t\u1ed1 l\u00e0m th\u00f4ng tin t\u0103ng l\u00ean v\u00e0 hi\u1ec7u qu\u1ea3 \u0111\u01b0\u1ee3c c\u1ea3i ti\u1ebfn, vi\u1ec7c ch\u1ea5p nh\u1eadn c\u00f4ng ngh\u1ec7 th\u00f4ng tin trong sinh h\u1ecdc v\u1eabn c\u00f2n t\u01b0\u01a1ng \u0111\u1ed1i m\u1edbi. T\u1eeb nh\u1eefng ng\u00e0y ti\u00ean phong s\u1edbm c\u1ee7a c\u00f4ng ngh\u1ec7 sinh h\u1ecdc trong nh\u1eefng n\u0103m 1970, con s\u1ed1 c\u00e1c kh\u00e1m ph\u00e1 v\u00e0 ph\u00e1t ki\u1ebfn h\u1ee9a h\u1eb9n \u0111\u00e3 \u0111\u01b0\u1ee3c nh\u00e2n l\u00ean b\u1ed9i ph\u1ea7n. Ng\u00e0y nay c\u00f3 tr\u00ean 200 li\u1ec7u ph\u00e1p v\u00e0 v\u1eafc xin \u0111\u00e3 \u0111\u01b0\u1ee3c t\u1ea1o ra qua c\u00f4ng ngh\u1ec7 sinh h\u1ecdc v\u00e0 ng\u00e0nh c\u00f4ng nghi\u1ec7p n\u00e0y nh\u01b0 m\u1ed9t to\u00e0n th\u1ec3 \u0111\u00e3 t\u0103ng tr\u01b0\u1edfng x\u1ea5p x\u1ec9 860% k\u1ec3 t\u1eeb 1994 th\u00e0nh m\u1ed9t \u0111\u1ec9nh th\u1ecb tr\u01b0\u1eddng to\u00e0n c\u1ea7u v\u1edbi gi\u00e1 tr\u1ecb x\u1ea5p x\u1ec9 $544 t\u1ec9 \u0111\u00f4 la trong n\u0103m 2014. Qua nh\u1eefng ph\u00e1t ki\u1ebfn v\u00e0 \u0111\u1ed9t ph\u00e1 ti\u1ec1m n\u0103ng trong ng\u00e0nh c\u00f4ng nghi\u1ec7p n\u00e0y c\u00f3 s\u1ed1 r\u1ea5t l\u1edbn c\u00e1c qui tr\u00ecnh ch\u01b0a \u0111\u01b0\u1ee3c ho\u00e0n thi\u1ec7n \u0111\u01b0\u1ee3c g\u1eafn k\u1ebft v\u1edbi s\u1ef1 thi\u00ean l\u1ec7ch, t\u1ed3n t\u1ea1i t\u1eeb l\u00e2u h\u01b0\u1edbng t\u1edbi nghi\u00ean c\u1ee9u v\u1ec1 th\u01b0\u01a1ng m\u1ea1i ho\u00e1 \u0111\u00e3 ng\u0103n c\u1ea3n ti\u1ec1m n\u0103ng s\u1eb5n c\u00f3 ch\u01b0a \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u0111\u1ea7y \u0111\u1ee7. Ch\u1eb3ng h\u1ea1n, vi\u1ec7c ph\u00e1t tri\u1ec3n thu\u1ed1c ng\u00e0y nay l\u00e0 r\u1ea5t t\u1ed1n k\u00e9m. Ph\u1ea3i t\u1ed1n h\u00e0ng tr\u0103m tri\u1ec7u \u0111\u00f4 la hay h\u01a1n ch\u1ec9 \u0111\u1ec3 l\u00e0m cho m\u1ed9t thu\u1ed1c qua \u0111\u01b0\u1ee3c th\u1eed l\u00e2m s\u00e0ng v\u00e0 ch\u1ea5p nh\u1eadn. Trong h\u00e0ng ngh\u00ecn thu\u1ed1c \u0111ang \u0111\u01b0\u1ee3c l\u00e0m vi\u1ec7c, ph\u1ea7n l\u1edbn ch\u1ec9 \u0111i m\u1ed9t ph\u1ea7n \u0111\u01b0\u1eddng r\u1ed3i ph\u1ea3i b\u1ecb b\u1ecf. B\u1eb1ng vi\u1ec7c \u00e1p d\u1ee5ng c\u00f4ng ngh\u1ec7 th\u00f4ng tin s\u1edbm trong qu\u00e1 tr\u00ecnh n\u00e0y, c\u00f3 th\u1ec3 thu \u0111\u01b0\u1ee3c th\u00f4ng tin v\u00e0 d\u1eef li\u1ec7u t\u1ed1t h\u01a1n \u0111\u1ec3 gi\u00fap c\u00e1c nh\u00e0 khoa h\u1ecdc l\u00e0m c\u00e1c quy\u1ebft \u0111\u1ecbnh hi\u1ec3u bi\u1ebft v\u00e0 gi\u1ea3m ph\u1ebf th\u1ea3i.<\/p>\n<p>Kh\u00e1m ph\u00e1 v\u00e0 ph\u00e1t tri\u1ec3n thu\u1ed1c ch\u1ec9 l\u00e0 m\u1ed9t v\u00ed d\u1ee5 n\u01a1i c\u00e1c ph\u00e1t ki\u1ebfn ph\u1ea7n m\u1ec1m \u0111\u1eb7c bi\u1ec7t c\u00f3 th\u1ec3 c\u00f3 kh\u1ea3 n\u0103ng h\u1ee3p l\u00ed ho\u00e1 b\u1ea3n ch\u1ea5t c\u00e1c qui tr\u00ecnh v\u00e0 n\u0103ng su\u1ea5t. B\u1eb1ng vi\u1ec7c \u00e1p d\u1ee5ng nhi\u1ec1u c\u00f4ng c\u1ee5 v\u00e0 ph\u01b0\u01a1ng ph\u00e1p ti\u00ean ti\u1ebfn, ng\u01b0\u1eddi ta c\u00f3 th\u1ec3 gi\u00fap kh\u00e9p l\u1ea1i k\u1ebd h\u1edf ph\u00e1t ki\u1ebfn gi\u1eefa c\u00e1c ho\u1ea1t \u0111\u1ed9ng nghi\u00ean c\u1ee9u v\u00e0 th\u01b0\u01a1ng m\u1ea1i ho\u00e1 trong sinh h\u1ecdc. Ph\u00e1t tri\u1ec3n th\u00e0nh c\u00f4ng ph\u00e1t ki\u1ebfn nh\u01b0 th\u1ebf s\u1ebd t\u1ea1o ra \u0111i\u1ec3m u\u1ed1n \u0111\u1ed9t ph\u00e1 trong ng\u00e0nh c\u00f4ng nghi\u1ec7p n\u00e0y, vi\u1ec7c n\u00e0y s\u1ebd s\u1edbm coi \u0111i\u1ec1u \u0111\u00f3 nh\u01b0 m\u1ed9t \u0111i\u1ec1u c\u1ea7n thi\u1ebft. N\u1ebfu l\u1ea5y ti\u1ebfn ho\u00e1 c\u1ee7a c\u00f4ng nghi\u1ec7p CNTT l\u00e0m c\u00e1i so s\u00e1nh h\u1ee3p l\u00ed, ng\u01b0\u1eddi ta c\u00f3 th\u1ec3 mong \u0111\u1ee3i s\u1ef1 sinh s\u00f4i n\u1ea3y n\u1edf c\u00f3 t\u00ednh b\u00f9ng ph\u00e1t c\u1ee7a ph\u1ea7n m\u1ec1m trong sinh h\u1ecdc khi nh\u1ea5n m\u1ea1nh d\u1ecbch chuy\u1ec3n t\u1eeb nghi\u00ean c\u1ee9u sang ph\u00e1t tri\u1ec3n s\u1ea3n ph\u1ea9m.<\/p>\n<p>&nbsp;<\/p>\n<p>&#8212;English version&#8212;<\/p>\n<p>&nbsp;<\/p>\n<p>Biotechnology: the new frontier<\/p>\n<p>After posting the articles: \u201cThe new revolution in Technology\u201d many students have asked me about the relationship between Biology and Information Technology, two completely different fields. The Biology field has changed significantly as the result of the Human Genome Project in 2000. Today scientists view Biology as an\u00a0 informational science, DNA is basically a digital four-letter language (C,T,G,A) storing information on chromosomes similar to the binary (0,1) in computer languages. Therefore, genes express themselves just like computers executing software programs. These expressions integrate with others to create a particular kind of \u201cinformational pathway\u201d that signals the body to perform certain function.<\/p>\n<p>Anything wrong with these pathway create problem or disease. By understand how these genes work, we can look at diseases from a different perspective. By understand the detail genes that predispose to disease, we can predict health history and it could change the way we treat disease today. Within our body, there are trillion of these interconnected \u201cinformational pathways\u201d that form networks. To understand this new view of biology, we have to understand these information at different levels, from cells to organs so we can understand how they work. If we understand these \u201cinformational pathways\u201d, we may be able to change them thus prevent disease from happening. This is the beginning of the new drug discovery principle.<\/p>\n<p>Today there is a convergent of Biology and Information Technology into a new field called Biotechnology because all the interactions within our body is really the information technology (IT) problems. That is why I believe all future biotechnology scientists should have knowledge of computer to work on their research. If we can define body systems through a mathematic modeling we can predict some emergent properties, and make a breakthrough in the way we deal with diseases. Of course, our body is a complex system and we only just begun to explore it from this new angle of information technology. Today in every research lab, there are many information available, some store at different databases, some at personal computers, and they have not been integrated, organized, categorized for further study. This is where I think information technology could add values. Even our brain is limited, we cannot process large and complex information but a computer can. It can process billion of data, sort through thousands of articles to find what we are looking for. With the use of computer and sophisticated algorithms, we can save significant amount of time in research. Instead of spending weeks and months finding the information that we need, we can use computer software to sort through and get to the right data, at the right time, to the right people.<\/p>\n<p>Five years ago, I created the Biotechnology Innovation program at Carnegie Mellon to apply information technology to enable biology and related fields to create valuable innovations that will help scientists to do their works faster and better. If we look back, we can see that information technology has led to significant changes across a wide variety of disciplines. Accounting, finance and manufacturing benefitted largely from software automation in the 1970s and 1980s. In the 1990s, advances in communication technologies helped to redefine how businesses managed their inventory, supply chains and how they relate with their customers. Many of these technologies and innovations have evolved from competitive differentiators to requisite competencies that are now essential to the operations of most companies.<\/p>\n<p>Though many industries have embraced information technology as an enabler of increased information and improved efficiency, adoption of information technology in the biology is still relatively new. Since the early pioneering days of biotechnology in the 1970s, the number of promising discoveries and innovations has multiplied dramatically. Today there are over 200 therapies and vaccines that have been created through biotechnology and the industry as a whole has grown approximately 860% since 1994 to a global market cap of approximately $544 billion in 2014. Though innovations and potential breakthroughs in the industry are incredibly numerous, immature processes coupled with a long standing, biased inclination towards research over commercialization have prevented the available potential from being fully realized. For example, today drug development is very expensive. It costs hundred million dollars or more just to get a drug through clinical trials and approval. Among thousands of drugs being worked on, most only got partially way through then had to be abandoned. By applying information technology early in the process, it is possible to obtain better information and data to help scientist making informed decision and reduce waste.<\/p>\n<p>Drug discovery and development is but one example where specific software innovations may be able to substantially streamline processes and productivity. By applying more advanced tools and methods, one can help close the innovation gap between research and commercialization activities in the biosciences. Successful development of such an innovation would create a disruptive inflection point in the industry that would soon regard it as a requisite necessity. If the evolution of the IT industry is any reasonable analogy, one can expect an explosive proliferation of software in the biology as emphasis shifts from research to product development.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sau khi \u0111\u0103ng b\u00e0i: \u201cCu\u1ed9c c\u00e1ch m\u1ea1ng m\u1edbi trong C\u00f4ng ngh\u1ec7\u201d nhi\u1ec1u sinh vi\u00ean \u0111\u00e3 h\u1ecfi t\u00f4i v\u1ec1 m\u1ed1i quan h\u1ec7 gi\u1eefa Sinh h\u1ecdc v\u00e0 &hellip; <\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-4708","post","type-post","status-publish","format-standard","hentry","category-xu-huong-cong-nghe"],"_links":{"self":[{"href":"https:\/\/science-technology.vn\/index.php?rest_route=\/wp\/v2\/posts\/4708","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/science-technology.vn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/science-technology.vn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/science-technology.vn\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/science-technology.vn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4708"}],"version-history":[{"count":1,"href":"https:\/\/science-technology.vn\/index.php?rest_route=\/wp\/v2\/posts\/4708\/revisions"}],"predecessor-version":[{"id":4709,"href":"https:\/\/science-technology.vn\/index.php?rest_route=\/wp\/v2\/posts\/4708\/revisions\/4709"}],"wp:attachment":[{"href":"https:\/\/science-technology.vn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4708"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/science-technology.vn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4708"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/science-technology.vn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4708"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}